Scottish firm Edinburgh Instruments, one of the leading manufacturers of high-performance molecular spectroscopy instruments, has launched the latest version of its research-grade, open-architecture, high-tech confocal Raman microscope - the RMS1000 model .
This versatile research instrument has been designed and built to accommodate almost any modern, state-of-the-art Raman spectroscopy application, but also enables other methods of investigating biochemical and biophysical systems such as time-resolved fluorescence (TRFM), fluorescence lifetime imaging (FLIM) and photoluminescence microscopy.
Key Features:
- 5 integrated lasers + possibility to add additional external lasers
- Flexibility in microscopy - upright and inverted microscope options
- Diffraction grating carousel with 5 positions
- Possibility to integrate up to two spectrographs
- Truly confocal - more than 10 pinhole positions available from 25 µm to 100 µm
- Motorised slitsize adjustable from 20 µm to 100 µm as standard, up to a maximum of 500 µm
- Motorised carousel for 6 Raman filters
- Filter wheel for laser intensity adjustment from 0.01% to 100%
- Up to four simultaneous detectors
- Internal standards and automatic calibration (Neon, Silicon, White light standards)
- User-friendly Ramacle® software for complete system control, data acquisition, display and analysis
- Additional methods available - photoluminescence microscopy, time-resolved fluorescence, FLIM
- System supplied with laser blocking when the instrument cover is opened - safety class Class I, or without laser cover - safety class 3B
This is a true confocal system with an adjustable motorized slit and multi-position adjustable pinhole for higher image resolution, better fluorescence suppression and overall application optimization. Compared to its predecessor, the RM5, on which the RMS1000 is based, the latest Raman microscope includes up to 5 integrated, computer-controlled narrowband lasers with the option to connect several additional external lasers. Pulsed lasers, either integrated directly into the system or connected externally, can also be used for fluorescence lifetime measurements (FLIM) and advanced Raman measurements.
The system includes up to two spectrographs, each with a 5 position carousel for diffraction gratings for the highest possible spectral resolution (from < 0.1 cm-1, coverage 5 cm-1 - 30,000 cm-1), suitable gratings are supplied with each laser. Up to 4 detectors can be installed - high efficiency TE-cooled CCD, EMCCD, InGaAs and others. Of course, integrated internal standards and auto-calibration procedures are provided to ensure the highest quality of acquired data, as well as the powerful Ramacle software package for complete system control, data acquisition and subsequent analysis. A major advantage for RMS1000 users is access to the KnowItAll Raman Identification Pro spectral library, which is available for material identification and advanced analysis. Data acquisition methods such as single measurements, multiple and accumulated scans, kinetic scans and map generation (depending on the accessory) are implemented with intuitive and user-friendly wizards.
For more information on this new feature, please refer to the enclosed brochure or the manufacturer's website.