FRAPPA (Fluorescence Recovery After Photo-bleach & Photo Activation) is one of the active illumination modules used to photostimulate cellular structures and tissues. This illumination element is compatible with SDCM (Spinning Disk Confocal Microscope) and other microscopes. FRAPPA uses a dual laser scanning head with a galvanometer for computer-controlled laser beam transmission. By using an Integrated Laser Engine (ILE) for a wide range of lasers and sharing them for imaging cellular structures, this illumination module can be used for more efficient bleaching in close proximity to the absorption peak of the targeted fluorophore. Major applications of the FRAPPA module include photo-bleaching, photoactivation, vesicle tracing, cell compartmentalization, targeted DNA damage (in cancer research), and uncaging.